COMPARISON OF METABOLIC PARAMETERS IN CHILDREN AND ADOLESCENTS WITH AND WITHOUT INSULIN RESISTANCE - (2019)
Acessos: 25
Leandro Coelho Lemos, Claudio Shigueki Suzuki, Aristides Miguel da Costa Machado-Rodrigues, William Cordeiro de Souza, Sandra Aires Ferreira, Adriana Masiero Kühl, Timothy Gustavo Cavazzotto, Marcos Roberto Queiroga, Luis Paulo Gomes Mascarenhas
Volume: 30 - Issue: 0
Resumo.
ABSTRACT The aim of the study was to compare the behavior of metabolic parameters, blood pressure, and obesity indicators in children and adolescents with and without insulin resistance. Sixty-one overweight children (6 to 18 years) underwent anthropometric measurements of body mass (BM), height and waist circumference (WC), blood pressure (BP), bioimpedance (relative (%F) and absolute fat (BF)), and blood collection for determination of glucose, insulin, and lipid profile (TG, CT, HDL-C, LDL-C). The BMI z-score was used to classify nutritional status and the HOMA-IR index (> 2.5) for insulin resistance. Participants were divided into two groups, insulin resistant (IR, n= 27) and non-insulin resistant (NIR, n= 33). Regardless of age, children and adolescents with excess weight and IR presented higher BM, WC, BMI, %F and BF (kg), TG, and plasma insulin than their NIR counterparts, who in turn presented higher LDL-C. The groups did not differ in nutritional status (BMI z-score); however, in the comparison between the undesired proportions of the metabolic components, only three presented alterations with significant differences between the groups (TC, LDL-C, and TG). It is concluded that IR influences the development of dyslipidemias in this age group, especially TG.
Keywords: Obesity, Adolescents, Metabolism
Idioma: English
Registro: 2024-08-17 14:46:30
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2448-24552019000100233&tlng=en
