Resumo. The aim of this experiment was to investigate the growth performance and physiological response of weaned pigs fed diets supplemented with a novel phytogenics (FCTNC). A total of 100 cross bred male pigs (Landrace × Duroc) with an initial weight of 6.31 ± 0.25 kg and weaned at 21 days were individually housed in a semi-open sided pens. Pigs were distributed into five treatments groups with five replicates, each replicates comprises of 20 pigs. Experimental diets were adequate in all nutrients recommended by NRC (2012). Treatment one (T1): basal diet without antibiotics; T2 (basal diet with neomycin at 1.5 g/kg-1); T3, T4 and T5 were fed basal diet with 5 g/kg-1, 10 g/kg-1 and 15 g/kg-1 respectively. Feed and water were offered unrestricted throughout the 56 days trial. Result revealed that there was effect of treatments (P ˂ 0.05) in average body weight gain (ADG), daily feed intake (ADFI), mortality and feed conversion ratio (FCR). Pigs in T4 (24.54 kg) and T5 (24.22 kg) had the highest weight gain, intermediate in T2 (21.55 kg) and T3 (22.51 kg) and lowest in T1 (12.83 kg) (P ˂ 0.05). There was a remarkable improvement in all the immune parameters examined among pigs fed FCTNC (P ˂ 0.05). Microbial population of Escherichia coli and Salmonella spp decreased as the level of FCTNC increases (P ˂ 0.05). Conversely, Lactobacillus spp count were highest in T4 and T5 relative to the other treatments. Haematological parameters were significantly influenced (P ˂ 0.05) by the treatments. However, all values were within the normal range for a clinically healthy pigs. The study established that FCTNC could be fed to weaned pigs up to 15 g/kg-1 without having any negative effect on the health of animals.