Resumo. The species Spondias tuberosa Arr. Cam. (umbuzeiro) stands out as one of the tree species with the greatest potential of the Brazilian semiarid. Even though it’s significant socioeconomic and environmental importance, there is a lack of studies aimed at establishing a seedlings production model of this kind of plant. The purpose of this study was to evaluate the production of seedlings Spondias tuberosa using different substrates and size of bags. The experiment was conducted in the nursery of the Plant Ecology Laboratory (LEV) from the Agrarian Sciences Center (CCA) of the Federal University of Paraiba (UFPB), Areia/ PB. The experimental design was a randomized block in factorial 2 x 7 and subdivided blocks containers plots and subplots substrates. It were used substrates formulated from the starting mixture of subsoil land (37.5-100%), sand (12.5-25%) and tanned cattle manure (10-50%). The containers used were black polyethylene bags with a volume of 1900 cm 3 (15 x 27 cm) and 5000 cm 3 (25 x 26 cm). To obtain seedlings of Spondias tuberosa seeds were sown in seed masonry until the transplant (90 days after sowing). At 78 days after transplanting the seedlings were evaluated for height, root collar diameter, relationship shoot/root collar diameter, xylopodium diameter, root length, dry weigh of shoot and root. The datas were subjected to analysis of variance and F test, measured and compared by Tukey test at 5% probability, using the software SISVAR ® . The substrates with cattle manure provided higher values for height and root length. For the seedlings production of Spondias tuberosa , is recommended substrate subsoil land (45%) + sand (15%) + cattle manure (40%).